Protein Details: Glycine receptor subunit alpha-2

Protein ID

ICDB_Pro_1161

Protein Name

Glycine receptor subunit alpha-2

Gene Name

Glra2

Organism

Mus musculus (Mouse)

Length

452 amino acids

AlphaFoldDB

AF-Q7TNC8-F1-model_v4.pdb

Function

Sequence

MYRQLVNILTALFAFFLGTNHFREAFCKDHDSRSGKHPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQMKDGTAVKATPANPLPQPPKDADAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

226;228;236-241;249;295

Disease

Location

Detected in the retina inner plexiform layer (at protein level). Detected in neonate retina. Detected in brain. Detected in spinal cord; with higher levels in the dorsal horn.